REVIEW PAPER
Renal function during metabolic acidosis
1
Department of Animal Physiology and Cytobiology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, Szczecin, Poland
Corresponding author
Anna Kurpińska
MSc. in Biology, Department of Animal Physiology and Cytobiology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, Doktora Judyma 6, 71-466 Szczecin, Poland.
MSc. in Biology, Department of Animal Physiology and Cytobiology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, Doktora Judyma 6, 71-466 Szczecin, Poland.
J Pre Clin Clin Res. 2010;4(1):1-4
KEYWORDS
ABSTRACT
Metabolic acidosis influences renal structural and functional changes that occur to restore acid-base homeostasis. In this review selected aspects of these changes are discussed, focusing especially on alternations in tubular reabsorption and excretion, changes in water homeostasis and induction of hypertrophy. Also highlighted is the usage of proteomic techniques and gene expression analysis as useful tools which facilitate the obtaining of a wider view on changes in the kidneys during metabolic acidosis.
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