REVIEW PAPER
Psychiatric disorders in women with polycystic ovary syndrome
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1
Department of General Surgery, Stefan Kardynał Wyszyński Province Specialist Hospital, Lublin, Poland
2
Faculty of Medicine, Medical University, Lublin, Poland
3
Orthopedics and Rehabilitation Clinic, University Clinical Hospital No.4, Lublin, Poland
4
Clinical Department of Toxicology, Cardiology and Internal Diseases, Stefan Kardynał Wyszyński Province Specialist Hospital, Lublin, Poland
5
II Department of General Surgery, Gastroenterology and Digestive System Cancer, University Clinical Hospital No.1, Lublin, Poland
6
Paediatric Department, Independent Public Health Care Centre, Wyszków, Poland
7
Clinical Department of Cardiac Surgery, University Clinical Hospital No.4, Lublin, Poland
These authors had equal contribution to this work
Corresponding author
Bernadeta Maliszewska
Department of General Surgery, Stefan Kardynał Wyszyński Province Specialist Hospital in Lublin, Kraśnicka 100 avenue, 20-718 Lublin, Poland
J Pre Clin Clin Res. 2024;18(3):286-292
KEYWORDS
TOPICS
ABSTRACT
Introduction and objective:
Polycystic ovary syndrome (PCOS) is one of the most common gynecological endocrine
disorders affecting women in reproductive age. Hyperandrogenism, oligoovulation, and polycystic ovaries seen on ultrasonography are its defining features. Women affected by PCOS are more susceptible to diabetes and dyslipidemia, as well as mental problems. Regarding the connection between PCOS and mental health, there are presently a number of theories. The aim of this study is to present the current knowledge of psychiatric disorders in women with PCOS, focusing on pathophysiology, molecular etiology and treatment.
Review methods:
A comprehensive literature review was performed using the electronic databases: PubMed, and Google
Scholar. Key words, such as: ‘PCOS’, ‘polycystic ovary syndrome’, ‘psychiatric’, ‘psychiatric disorders’ and various combinations of the above were used. The search was limited by the year 2010 for all keywords.
Brief description of the state of knowledge:
It is known that PCOS is linked to an increased prevalence of depression, bipolar disease, anxiety disorder and eating disorder. The literature review shows that the gut-brain axis, neurotransmitter and neuroendocrine dysfunction play significant roles in pathogenesis on the co occurrence of mental diseases and PCOS.
Summary:
Despite the potential socio-economic impact psychiatric disorders may have on PCOS patients and society,
only a limited amount of research has been undertaken to investigate this relationship. The need for screening tests for all women with PCOS for mental disorders and adequately treat women diagnosed with these conditions is emphasized.
Maliszewska B, Tokarzewska A, Łasica M, Małyszek M, Łaba Ł, Dziurda S, Łomża-Łaba AW, Łuczyński D. Psychiatric disorders in women with
Polycystic Ovary Syndrome. J Pre-Clin Clin Res. 2024; 18(3): 286–292. doi: 10.26444/jpccr/192128
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