CASE REPORT
Necrosis BRONJ of the mandible, complicated by Actinomyces infection – Case Report
1
Department of Maxillofacial Surgery. Medical University of Lublin, Poland
2
Medical University of Lublin, Poland
Corresponding author
Anna Gaweda
Department of Maxillofacial Surgery. Medical University of Lublin, The Medical University of Lublin, Staszica 11, 20-081 Lublin, Poland, 20-081 Lublin, Poland
Department of Maxillofacial Surgery. Medical University of Lublin, The Medical University of Lublin, Staszica 11, 20-081 Lublin, Poland, 20-081 Lublin, Poland
J Pre Clin Clin Res. 2018;12(3):82-86
KEYWORDS
bisphosphonate-related osteonecrosis of the jawsbiphosphonatesactinomycosissurgical debridementantibiotic therapy
TOPICS
ABSTRACT
Biphosphonate-related osteonecrosis of the jaw (BRONJ) is a common complication of the therapy of malignant cancers. Drugs improve bone density and reduce hypercalcaemia in patients with primary tumours, as well as their metastases to the bones. A characteristic feature are emerging foci of osteonecrosis of the jaws, with secondary infection which is
often actinomycotic. Actinomyces are Gramm-positive bacteria which colonize the mucous membrane and in favourable conditions are the cause of inflammation. BRONJ appears spontaneously or may be a consequence of surgical treatment in the area of the jaws. The case is presented of an 82-year-old woman after hysterectomy due to a cancerous lesion who
had taken ibandronic acid for a long time. Because of the severe pain in the mandible and the advanced disease, surgical sequestration of the necrosis and antibiotic treatment of the actinomycosis were necessary.
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| ISSN: | 1898-2395 |
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