Ectopic and heterotopic both refer to cells displaced from their normal site – ectopic cells occur outside their organ of
origin whereas heterotopic cells are in an aberrant location within their organ of origin. The most common localization
of heterotopic neuroglial tissue (HNT) is the nasal region. We report a case of 69-years-old man who presented with long
history of lumbosacral pain with paresis of the inferior limb. MRI examination detected a cystic tumour located at the L1-L2
level. Histologic examination revealed the presence of heterotopic neuroglial tissue, containing synaptophysin, glial cells
and encircled meninges.
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Sarnat HB: Ectopic or heterotopic? An appeal for semantic precision in describing developmental disorders of the nervous system. Pediatr Neurol.1995;13:178–179.
Hendrickson M, Faye-Petersen O, Johnson DG: Cystic and solid heterotopic brain in the face and neck: a review and report of an unusual case. J Pediatr Surg.1990; 25:766–768.
Wolbach SB: Congenital rhabdomyoma of the heart. Report of a case associated with multiple nests of neuroglia tissue in the meninges of the spinal cord. J Med Res.1907;16;495–520.
Penner CR, DDS, Thompson LRD. Nasal Glial. Heterotopia: A Clinicopathologic and Immuno phenotypic Analysis of 10 Cases With a Review of the Literature. Annals of Diagnostic Pathology. 2003;7(6):354–359.
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