CASE REPORT
Gullo’s Syndrome – case report
1
Department of Gastroenterology with Endoscopy Unit, Medical University, Lublin, Poland
2
Gastroenterology Unit, Independent Public Teaching Hospital No. 4, Lublin, Poland
Corresponding author
J Pre Clin Clin Res. 2020;14(4):117-119
KEYWORDS
amylaselipaseGullo’s Syndromebenign pancreatic hyperenzymemia (BPH)elevated pancreatic enzyme activitypancreatic hyperenzymemiapancreatic enzymes (PE)
TOPICS
ABSTRACT
Benign pancreatic hyperenzymemia (BPH) or Gullo’s Syndrome is a persistent elevation of pancreatic enzymes activity, observed for at least one year, with no pancreatic disorder. This diagnosis is extremely important because it allows us to avoid many unnecessary examinations performed during the diagnostic process. The case is presented of a 25-year-old man who was examined for recurrent elevated lipase and amylase serum values over a time period of 2 years who presentedwith non-specific abdominal complaints. Interestingly, his routine tests showed sustained elevated serum amylase and lipase activity. He was intensively diagnosed due to pancreatic hyperenzymemia, but no pancreatic disease was detected. The observation lasted two years. The serum lipase and serum amylase levels continued to increase after that time. This diagnosis requires attention because BPH can be the first symptom of pancreatic cancer.
ABBREVIATIONS
BPH – benign pancreatic hyperenzymemia
PE – pancreatic enzymes
HIV – human immunodeficiency virus
CEA – carcinoembryonic antigen
CA19-9 – carbohydrate antigen 19-9
AFP – alpha-fetoprotein
CA125 – carbohydrate antigen 125
NOD2 – nucleotide-binding oligomerization domain
containing 2
PRSS1 – serine protease 1
SPINK1 – serine protease inhibitor Kazal-type 1
CAPH – chronic asymptomatic pancreatic hyperenzymemia
EUS – endoscopic ultrasonography
s-MRCP – secretin-magnetic resonance cholangiopancreatography
MRCP – magnetic resonance cholangio-pancreatography
FUNDING
No funding was received.
CONFLICT OF INTEREST
The authors declare that they have no competing interests.
Rycyk A, Furtak P, Mądro A, Kasztelan-Szczerbińska B, Cichoż-Lach H. Gullo’s Syndrome: case report. J Pre-Clin Clin Res. 2020; 14(4): 117–119. doi: 10.26444/jpccr/127792
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| eISSN: | 1898-7516 |
| ISSN: | 1898-2395 |
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