CASE REPORT
Delayed HIV diagnosis of patients due to the COVID-19 pandemic
1
Department of Infectious Diseases, Medical University, Lublin, Poland
Corresponding author
Anna Sobstyl
Department of Infectious Diseases, Medical University of Lublin, Poland, Lublin, Poland
Department of Infectious Diseases, Medical University of Lublin, Poland, Lublin, Poland
J Pre Clin Clin Res. 2022;16(2):42-44
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The AIDS disease epidemic is still a global problem. To date, finding the connection between HIV and SARSCoV-2 infection is very significant.
Case Report:
A 51-year-old woman was admitted to the Neurology Department due to neurological symptoms lasting for 1.5 months. Imaging examinations of the CNS, chest CT and cerebrospinal fluid examination revealed significant abnormalities. Tests for HIV and SARS-CoV-2 were both positive. Klebsiella pneumoniae ESBL+ was detected in rectal swab as well as findings of Candida antigens and antibodies of Cryptococcus neoformans mycosis in serum. Due to these results, appropriate treatment was implemented but with with a time delay which resulted in the death of the patient.
Conclusions:
HIV infection may be associated with an increased risk of severe SARS-CoV-2 infection causing an increase in mortality rate during the COVID-19 pandemic. Confirmation and early detection of HIV infection permits early and accurate diagnosis and faster treatment decisions.
The AIDS disease epidemic is still a global problem. To date, finding the connection between HIV and SARSCoV-2 infection is very significant.
Case Report:
A 51-year-old woman was admitted to the Neurology Department due to neurological symptoms lasting for 1.5 months. Imaging examinations of the CNS, chest CT and cerebrospinal fluid examination revealed significant abnormalities. Tests for HIV and SARS-CoV-2 were both positive. Klebsiella pneumoniae ESBL+ was detected in rectal swab as well as findings of Candida antigens and antibodies of Cryptococcus neoformans mycosis in serum. Due to these results, appropriate treatment was implemented but with with a time delay which resulted in the death of the patient.
Conclusions:
HIV infection may be associated with an increased risk of severe SARS-CoV-2 infection causing an increase in mortality rate during the COVID-19 pandemic. Confirmation and early detection of HIV infection permits early and accurate diagnosis and faster treatment decisions.
Sierpień M, Sobstyl A, Sergiel N, Górska D, Stempkowska-Rejek J, Tomasiewicz K. Delayed HIV diagnosis of patients due to COVID-19
pandemic. J Pre-Clin Clin Res. 2022; 16(2): 42–44. doi: 10.26444/jpccr/150518
REFERENCES (17)
1.
Gazzard B. AIDS. Baillieres Clin Gastroenterol. 1987;1(3):567–587. https://doi.org/10.1016/0950–3....
2.
UNAIDS report shows that people living with HIV face a double jeopardy, HIV and COVID-19, while key populations and children continue to be left behind in access to HIV services. https://www.unaids. org/en/resources/presscentre/pressreleaseandstatementarchive/2021/ july/20210714_global-aids-update (access: 2021.07.19).
3.
Lehmann C, Malin J, Suárez I, et al. Moderne HIV-Therapie. Internist. 2019;60(4):411–419. https://doi.org/10.1007/s00108....
4.
Wójcik-Cichy K, Jabłonowska O, Piekarska A, et al. The high incidence of late presenters for HIV/AIDS infection in the Lodz province, Poland in the years 2009–2016: we are still far from the UNAIDS 90% target. AIDS Care. 2018;30(12):1538–1541. https://doi.org/10.1080/095401....
5.
Kowalska JD, Skrzat-Klapaczyńska A, Bursa D, et al. HIV care in times of the COVID-19 crisis — Where are we now in Central and Eastern Europe? Int J Infect Dis. 2020;96:311–314. https://doi.org/10.1016/j. ijid.2020.05.013.
6.
Kanwugu ON, Adadi P. HIV/SARS-CoV-2 coinfection: A global perspective. J Med Virol. 2020;10.1002/jmv.26321. https://doi. org/10.1002/jmv.26321.
7.
Kendall CE, Shoemaker ES, Raboud J, et al. Assessing Timely Presentation to Care Among People Diagnosed with HIV During Hospital Admission: A Population-Based Study in Ontario, Canada. AIDS Behav. 2018;22(8):2575–2583. https://doi.org/10.1007/s10461....
8.
Raben D, Sullivan AK, Mocroft A, et al. Improving the evidence for indicator condition guided HIV testing in Europe: Results from the HIDES II Study – 2012 – 2015. PLoS ONE. 2019;14(8):e0220108. https:// doi.org/10.1371/journal.pone.0220108.
9.
Bull L, Rayment M. HIV-indicator-condition-driven HIV testing: clinically effective but still rarely implemented. Clin Med. 2016;16(2):175–179. https://doi.org/10.7861/clinme....
10.
Ahee A van, Combs K, Delpech V, et al. Public Health Guidance on HIV, Hepatitis B and C Testing in the EU/EEA: An Integrated Approach; 2018. http://dx.publications.europa..... (access 2021.07.19).
11.
Thakur KT. CNS infections in HIV. Curr Opin Infect Dis. 2020;33(3):267–272. https://doi.org/10.1097/QCO.00....
12.
Cribbs SK, Crothers K, Morris A. Pathogenesis of HIV-Related Lung Disease: Immunity, Infection, and Inflammation. Physiol Rev. 2020;100(2):603–632. https://doi.org/10.1152/physre....
13.
Joob B, Wiwanitkit V. SARS-CoV-2 and HIV. J Med Virol. March 2020;10.1002/jmv.25782. https://doi.org/10.1002/jmv.25....
14.
Baluku JB, Mwebaza S, Ingabire G, et al. HIV and SARS-CoV-2 coinfection: A case report from Uganda. J Med Virol. 2020;10.1002/ jmv.26044. https://doi.org/10.1002/jmv.26....
15.
Ssentongo P, Heilbrunn ES, Ssentongo AE, et al. Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis. Sci Rep. 2021;11:6283. https://doi.org/10.1038/ s41598-021-85359-3.
16.
Maziarz EK, Perfect JR. Cryptococcosis. Infect Dis Clin North Am. 2016;30(1):179–206. https://doi.org/10.1016/j.idc.....
17.
Huang J, Xie N, Hu X, et al. Epidemiological, virological and serological features of COVID-19 cases in people living with HIV in Wuhan City: A population-based cohort study. Clin Infect Dis Off Publ Infect Dis Soc Am. 2020;ciaa1186. https://doi.org/10.1093/cid/ci....
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