CASE REPORT
Cryoapplication and laser treatment in oral precancerous lesions – case report and literature review
1
Department and Clinic of Maxilofacial Surgery, Medical University, Lublin, Poland
2
Department of Dental Surgery, Medical University, Lublin, Poland / Student Research Group at the Department of Dental Surgery, Medical University, Lublin, Poland
Corresponding author
Kamila Smala
Student Research Group at the Department of Dental Surgery, Medical University, Chodźki, 20–093 Lublin, Poland
Student Research Group at the Department of Dental Surgery, Medical University, Chodźki, 20–093 Lublin, Poland
J Pre Clin Clin Res. 2024;18(4):353-357
KEYWORDS
TOPICS
ABSTRACT
Cryoapplication, a rarely used dental technique, freezes lesional tissues to disrupt them at the cellular level. The technique
iss minimally invasive and suitable for specific mucosal lesions, offering a conservative option for oral pre-cancers. Studies
show that cryotherapy is promising for managing pre-cancerous lesions with few complications. Cryogun and cottonswab
cryotherapy effectively regress oral leukoplakia lesions. Cryotherapy advantages include bloodless application and
less scarring potential, making it suitable for mucosal alterations. More research is needed to define indications, optimize
use in oral pre-cancers, and address limitations to enhance outcomes compared to alternatives. This paper presents a case
of treating white rough lesions on a 59-year-old female’s oral mucosa using cryoapplication and laser, and reviews their
efficacy in managing oral leukoplakia and pre-cancerous conditions.
Świątkowski W, Smala K, Bis E, Rahnama-Hezavah M. Cryoapplication and laser treatment in oral precancerous lesions – case report and literature review. J Pre Clin-Clin Res. 2024; 18(4): 353–357. doi: 10.26444/jpccr/195944
REFERENCES (13)
1.
Yu CH, Lin HP, Cheng SJ, Sun A, Chen HM. Cryotherapy for oral precancers and cancers. J Formos Med Assoc. 2014 May;113(5):272–277. doi:10.1016/j.jfma.2014.01.014. PMID:24560447.
2.
Trichard S, Dantony E, Maucort-Boulch D, Gueugniaud P, Piriou V, Ecochard R, Busseuil C. Essai randomisé évaluant l’utilisation de la cryothérapie seule ou en association avec des antalgiques dans la prise en charge de la douleur en traumatologie d’urgence. Ann Anat. 2016;6:1–8. doi:10.1007/s13341-016-0692-2.
3.
Lodi G, Franchini R, Warnakulasuriya S, Varoni EM, Sardella A, Kerr AR, Carrassi A, MacDonald LCI, Worthington HV. Interventions for treating oral leukoplakia to prevent oral cancer. Cochrane Database Syst Rev. 2016;(7). doi:10.1002/14651858.CD001829.pub4.
4.
Liu W, Zhang X, Shi L, Shen X. Whether cryosurgery for oral premalignant lesions influences the outcome of malignant transformation. Int J Surg. 2023 Oct;109(10):3219–3221. doi:10.1097/JS9.0000000000000549.
5.
Yu CH, Chen HM, Chang CC, Hung HY, Hsiao CK, Chiang CP. Cotton-swab cryotherapy for oral leukoplakia. Head Neck. 2009 Aug;31(8):983–988. doi:10.1002/hed.21055. PMID:19283844.
6.
Arora KS, Bansal R, Mohapatra S, et al. Prevention of malignant transformation of oral leukoplakia and oral lichen planus using laser: an observational study. Asian Pac J Cancer Prev. 2018 Dec;19(12):3635–3641. doi:10.31557/apjcp.2018.19.12.3635. PMID:30583693; PMCID:PMC6428544.
7.
Condor D, Culcițchi C, Blum R, Baru O, Buduru S, Kui A, Țig I. A Review of CO2 Laser-Mediated Therapy for Oral Mucosal Lesions. Applied Sciences. 2021;11(16):7744. https://doi.org/10.3390/app111....
8.
Natekar M, Raghuveer HP, Rayapati DK, Shobha ES, Prashanth NT, Rangan V, Panicker AG. A comparative evaluation: oral leukoplakia surgical management using diode laser, CO2 laser, and cryosurgery. J Clin Exp Dent. 2017 Jun;9(6). doi:10.4317/jced.53602. PMID:28638555; PMCID:PMC5474334.
9.
Pandey A. Cryotherapy for oral potentially malignant disorders. Bioinformation. 2023;19:1377–1382. doi:10.6026/973206300191377.
10.
Kawczyk-Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A, Kwiatek S, Straszak D, Latos W, Koszowski R, Sieroń A. Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia. Photodiagnosis Photodyn Ther. 2012 Jun;9(2):148–155. doi:10.1016/j.pdpdt.2011.12.007. PMID:22594985.
11.
Aggarwal N, Ahuja K, Pal N, Pannu R, Berwal V, Neeraj. Cryosurgery: a therapeutic modality for oro-facial lesions. Int J Community Health Med Res. 2017;3(3):66. Available at: http://www.ijchmr.com/index.ph.... Accessed June 23, 2024.
12.
Chen Q, Dan H, Pan W, et al. Management of oral leukoplakia: a position paper of the Society of Oral Medicine, Chinese Stomatological Association. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Jul;132(1):32–43. doi:10.1016/j.oooo.2021.03.009. PMID:34006487.
13.
Andabak-Rogulj A, Vindiš E, Aleksijević LH, Škrinjar I, Juras DV, Aščić A, Brzak BL. Different treatment modalities of oral lichen planus—a narrative review. Dent J. 2023;11:26. doi:10.3390/dj11010026.
| eISSN: | 1898-7516 |
| ISSN: | 1898-2395 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
