Cervicofacial actinomycosis is a specific, primarily chronic inflammatory process caused by Gram-positive anaerobic, microaerophilic Actinomyces bacteria. The infection usually results from the skin or mucosal lesions. The following paper reports two cases of Cervicofacial actinomycosis in patients admitted in 2014 to Maxillofacial Surgery Department in Lublin, Poland. Diagnosis of culture-positive actinomycosis was based on histopathology findings and the presence of actinomyces colonies. Cervicofacial actinomycosis requires surgical treatment, oral cavity sanation, and in the case of presenting actinomycosis abscesses formation, combined surgical incision and drainage. Long-term penicillin antibiotic therapy is necessary.