Introduction and objective:
Skeletal Class III malocclusion, characterized by complex craniofacial irregularities, often necessitates orthognathic interventions for its resolution. The aims of the study were 1) to comprehensively assess the dimensions of the upper airway and cephalometric measurement, 2) to evaluate the values of upper airway dimensions in a three-dimensional context, in correlation with cephalometric measurements acquired in a two-dimensional format among patients afflicted with skeletal Class III malocclusion.

Material and methods:
Medical records were analysed of 18 patients diagnosed with skeletal Class III malocclusion undergoing combined orthodontic-surgical treatment. Cephalometric measurements were extracted from lateral cephalometric radiographs, and upper airway dimensions comprehensively evaluated using multi-slice spiral computed tomography scans and OsiriX software. Based on the results statistical analysis was performed.

Results:
No statistically significant correlations was found between the cephalometric measurements using two-dimensional cephalometry and the upper airway dimensions using three-dimensional computed tomography in patients with skeletal Class III malocclusion.

Conclusions:
No direct influence of skeletal Class III malocclusion on upper airway dimensions was observed in study participants. Incorporating additional factors, such as soft tissue characteristics and functional aspects, may provide a more comprehensive understanding of the relationship between skeletal malocclusion and upper airway dimensions.